The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2003
Filed:
Aug. 30, 2001
Brian Weston Dalder, West Lafayette, IN (US);
Michael Anthony Dotlich, Lafayette, IN (US);
Neil John Kallman, Lafayette, IN (US);
Samuel Dean Larsen, West Lafayette, IN (US);
Sharon Van Den Berghe Snorek, Lafayette, IN (US);
Jeffrey Thomas Vicenzi, Brownsburg, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
A method is described for forming a crystalline Echinocandin nucleus salt from its mixed broth and/or partially purified process streams by the steps of nanofiltration to form a concentrate, addition of an aldehyde derivatizing agent which interacts with an aldehyde impurity, addition of an acid/metal salt to form a solubilized echinocandin nucleus salt having the desired anion, and subsequent cooling of the mixture to crystallize the salt.