The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2003
Filed:
May. 09, 2002
Krishnaswamy S. Raghavan, Cranbury, NJ (US);
Sunanda A. Ranadive, East Brunswick, NJ (US);
Kenneth S. Bembenek, Dayton, NJ (US);
Loutfy Benkerrour, Paris, FR;
Veronique Trognon, La Turballe, FR;
Richard G. Corrao, Jackson, NJ (US);
Luigi Esposito, Howell, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
There is provided in accordance with the present invention the quinolone antibacterial gatifloxacin adequately taste-masked so that it can be utilized for pediatric formulations. A crystalline co-precipitate of gatifloxacin and one or both of stearic acid and palmitic acid in a narrow weight ratio has been found to effectively mask the bitter taste of gatifloxacin. The taste of gatifloxacin is effectively masked in the mouth and in aqueous suspension through a full dosage cycle, typically fourteen days. Gatifloxacin in the subject crystalline co-precipitates has been found to be readily available for absorption from the stomach.