The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2003

Filed:

Aug. 10, 2000
Applicant:
Inventors:

Mauro Napoletano, Milan, IT;

Gabriele Norcini, Vizzola Ticino, IT;

Daniela Botta, Como, IT;

Giancarlo Grancini, Nova Milanese, IT;

Gabriele Morazzoni, Lainate, IT;

Francesco Santangelo, Milan, IT;

Jorge G. Siro Herrero, Calà d'Henares, ES;

José Luis Garcia Navaio, Madrid, ES;

Julio G. Alvarez-Builla, Madrid, ES;

Assignee:

Zambon Group S.p.A., Vincenza, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1502 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1502 ; C07D / ;
Abstract

Compounds of formula (I) wherein B is alkylene, amino, CONH or a bond; Cy is optionally substituted phenyl or heteroaryl; R is H, phenyl or (C )alkyl optionally substituted; R is (C )alkyl or polyfluoro(C )-alkyl; R is (C )cycloalkyl optionally containing an oxygen atom and optionally substituted; and the N→O derivatives and pharmaceutically acceptable salt thereof are PDE 4 and TNF&agr; inhibitors.


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