The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2003

Filed:

Nov. 28, 2000
Applicant:
Inventors:

Bernard Malfroy-Camine, Arlington, MA (US);

Susan Doctrow, Roslindale, MA (US);

Assignee:

Eukarion, Inc., Bedford, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/1555 ; A61K 3/128 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1555 ; A61K 3/128 ; C07D / ;
Abstract

This invention provides antioxidant cyclic salen-metal compounds, compositions of such antioxidant cyclic salen-metal compounds having superoxide activity, catalase activity and/or peroxidase activity and methods of using such antioxidant cyclic salen-metal compositions to treat or prevent a disease associated with cell or tissue damage produced by free radicals, such as superoxide. In one embodiment, the present invention provides cyclic salen-metal compounds having the following general formula:


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