The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2003

Filed:

Mar. 08, 2001
Applicant:
Inventors:

Kevin A. Babiak, Evanston, IL (US);

Andrew Carpenter, Zebulon, NC (US);

Shine Chou, St. Louis, MO (US);

Pierre-Jean Colson, Skokie, IL (US);

Payman Farid, Vernon Hills, IL (US);

Robert Hett, Aarau, CH;

Christian H. Huber, Skokie, IL (US);

Kevin J. Koeller, Maryland Heights, MO (US);

Jon P. Lawson, Glencoe, MO (US);

James Li, Pennington, NJ (US);

Eduardo K. Mar, Northbrook, IL (US);

Lawrence M. Miller, Des Plaines, IL (US);

Vladislav Orlovski, Wheeling, IL (US);

James C. Peterson, Manchester, MO (US);

Mark J. Pozzo, Chesterfield, MO (US);

Claire A. Przybyla, Des Plaines, IL (US);

Samuel J. Tremont, St. Louis, MO (US);

Jay S. Trivedi, Skokie, IL (US);

Grace M. Wagner, Webster Groves, MO (US);

Gerald A. Weisenburger, Evanston, IL (US);

Benxin Zhi, Newbury Park, CA (US);

Assignee:

G.D. Searle, LLC, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1495 ; A61K 3/138 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1495 ; A61K 3/138 ; C07D / ; C07D / ;
Abstract

Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds.


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