The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 01, 2003

Filed:

Jun. 18, 2002
Applicant:
Inventors:

Jonathan K. Leach, Norman, OK (US);

Edgar O'Rear, Norman, OK (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/16 ; A61K 9/50 ;
U.S. Cl.
CPC ...
A61K 9/16 ; A61K 9/50 ;
Abstract

A drug delivery system which includes a plurality of microcapsules, each microcapsule containing a plasminogen activator entrapped in a biocompatible, biodegradable, substantially water-soluble polymeric matrix such that the plasminogen activator is releasable therefrom upon exposure of the microcapsules to an aqueous environment, as well as methods for preparing same. Methods of treating a thrombotic condition and reducing the time required for reperfusion of an occluded blood vessel are also described, which include parenterally administering to a mammal a therapeutically effective amount of a pharmaceutical composition which includes a plurality of such microcapsules.


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