The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 24, 2003
Filed:
Apr. 17, 2002
Applicant:
Inventors:
Maurizio Zenoni, Paullo, IT;
Alessandro Donadelli, Casalpusterlengo, IT;
Marco Silvagni, Segrate, IT;
Assignee:
ACS Dobfar S.p.A., Tribiano, IT;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
C07D / ;
Abstract
A safe and economical process for obtaining salts of 4-carboxy-3-hydroxy-5-mercapto-isothiazole. This process comprises refluxing a disodium or dipotassium salt of 3-hydroxy-5-mercapto-4-isothiazole carbonitrile in an aqueous solution of sodium or potassium hydroxide to produce the desired salt. The desired salt may be precipitated out of solution by adjusting the pH downward to a minimum value of about pH 8. Compounds produced by this process may be used for producing semi-synthetic cephalosporins.