The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2003
Filed:
Mar. 18, 2002
Applicant:
Inventors:
Gary Keith Smith, Raleigh, NC (US);
David Stanley Duch, Cary, NC (US);
Robert Ferone, Raleigh, NC (US);
Arthur Koch, Bloomington, IN (US);
Assignee:
SmithKline Beecham Corporation, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1495 ; A61K 3/150 ; A61K 3/1505 ;
U.S. Cl.
CPC ...
A61K 3/1495 ; A61K 3/150 ; A61K 3/1505 ;
Abstract
The use of a protecting agent, for example a folate derivative such as folic acid or leucovorin, in combination with a non-competitive folic acid analogue, for example benzoquinazoline derivatives, for use in reducing the side effects associated with the administration of such non-competitive folic acid analogues, and pharmaceutical formulations comprising such combinations are disclosed.