The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2003

Filed:

Aug. 04, 2000
Applicant:
Inventors:

Stephen T. Yue, Eugene, OR (US);

Thomas H. Steinberg, Eugene, OR (US);

Wayne F. Patton, Eugene, OR (US);

Ching-Ying Cheung, Eugene, OR (US);

Richard P. Haugland, Eugene, OR (US);

Assignee:

Molecular Probes, Inc., Eugene, OR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/348 ; G01N 3/352 ; G01N 3/368 ;
U.S. Cl.
CPC ...
G01N 3/348 ; G01N 3/352 ; G01N 3/368 ;
Abstract

The present invention describes a variety of substituted and unsubstituted carbazolylvinyl dyes and their use for detecting and quantifying poly(amino acids), including peptides, polypeptides and proteins. The labeled proteins or peptides are highly colored, but are also detected by their strong fluorescence enhancement. Poly(amino acids) are detected in solution, in electrophoretic gels, and on solid supports, including blots and dipsticks. The present method of staining is highly sensitive, extremely facile, and relatively non-selective and can be accomplished without the use of organic solvent additives.


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