The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2003

Filed:

Nov. 18, 1999
Applicant:
Inventor:

Kenji Kohno, Nara, JP;

Assignee:

DNAVEC Research Inc., Ibaraki, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 6/700 ; A01K 6/7027 ; C12N 5/00 ; C12N 1/500 ; C12N 1/563 ;
U.S. Cl.
CPC ...
A01K 6/700 ; A01K 6/7027 ; C12N 5/00 ; C12N 1/500 ; C12N 1/563 ;
Abstract

Transgenic mice are constructed by binding the “hHB-EGF/DTR” gene to the downstream of an albumin enhancer/promoter that is expressed specifically in hepatic parenchymal cells and introducing this unit into mice. After the “hHB-EGF/DTR” gene has been confirmed to be expressed specifically in hapatic cells, diphtehria toxin is administered to the transgenic mice to examine whether the hepatic parenchymal cells are disrupted. The hepatic cells of the transgenic mice can be selectively dirupted depending on the administration period of the diphtheria toxin.


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Kohno, Kenji. (2003). Knockout animals (U.S. Patent No. 6576813). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6576813

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