The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2003
Filed:
May. 21, 2001
Applicant:
Inventors:
Martin Stogniew, Blue Bell, PA (US);
Javad M. Zadei, West Chester, PA (US);
Assignee:
MedImmune Oncology, Inc., Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1505 ; A61K 3/1517 ;
U.S. Cl.
CPC ...
A61K 3/1505 ; A61K 3/1517 ;
Abstract
This invention is directed to the novel composition of matter trimetrexate ascorbate, to compositions comprising trimetrexate ascorbate, and to compositions comprising trimetrexate and ascorbic acid. These compositions are useful in the treatment of diseases in mammals such as, but not limited to, cancer, bacterial and protozoal infections, malaria, psoriasis, and rheumatoid arthritis. The invention is further related to methods of stabilizing trimetrexate to degradation caused by heat, light, oxygen, or water.