The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2003
Filed:
May. 28, 2002
Applicant:
Inventors:
C. George Carlson, Kirksville, MO (US);
James L. Cox, Kirksville, MO (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/324 ; C12N 5/00 ; C12Q 1/02 ;
U.S. Cl.
CPC ...
A61K 3/324 ; C12N 5/00 ; C12Q 1/02 ;
Abstract
A method is provided for inhibiting and substantially decreasing the motility of cells, and especially melanoma cells. In the invention, a cell is contacted with a motility-inhibiting amount of a metal ion selected from the group consisting of cobalt ion, the lanthanide metal ions, and mixtures thereof; particularly preferred metal ions are the Co and Gd ions. Metal ion sources may be administered in the form of soluble metal halide salts to in vitro to cells dispersed in an aqueous saline medium, or by administering an aqueous dispersion thereof to an in vivo mammalian subject at or adjacent a tumor site.