The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2003

Filed:

Mar. 09, 2001
Applicant:
Inventors:

Nami Sugita, Ranzan, JP;

Kenichi Kawabata, Kodaira, JP;

Shinichiro Umemura, Hachioji, JP;

Kazuaki Sasaki, Kokubunji, JP;

Isao Sakata, Okayama, JP;

Assignee:

Hitachi, Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 8/00 ; C07D / ;
U.S. Cl.
CPC ...
A61B 8/00 ; C07D / ;
Abstract

A sensitizer for tumor treatment has a structure such that a lipophilic group and a hydrophilic group are bound to one and the same carbon atom in a compound containing a xanthene dye structure. It is important that the lipophilic group and hydrophilic group are bound to one and the same carbon atom; if they are separated from each other, no sufficient effect is obtained. Thus, the sensitizer possesses both lipophilicity and hydrophilicity. This sensitizer has a function of promoting acoustic cavitation and a function of revealing an antitumor effect and is an agent highly accumulable in tumor tissues. Thus, this sensitizer is highly selective for tumor tissues and enables the treatment of malignant tumor using ultrasound.


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