The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2003

Filed:

Jan. 30, 2002
Applicant:
Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K 3/1165 ;
U.S. Cl.
CPC ...
C07C / ; A61K 3/1165 ;
Abstract

A compound of formula (I): or a salt thereof, or a solvate thereof, wherein Ar represents substituted or unsubstituted aryl, wherein the optional substituents are selected from alkyl, hydroxy or alkoxy or, if attached to adjacent carbon atoms any two substituents together with the carbon atoms to which they are attached may form a fused heterocyclic ring of five to six atoms wherein one, two or three of the said atoms are oxygen or nitrogen; A represents a C n-alkylene group wherein each carbon is optionally substituted by 1 or 2 C alkyl groups; R represents hydrogen, alkyl, alkenyl or cycloalkyl; one or two of of the group of R , R and R represents nitro the remaining members of the group of R , R and R represent hydrogen; X represents a —CO—NH— moiety; and Z represents C n-alkylene group wherein each carbon is optionally substituted 1 or 2 C alkyl groups; a process for preparing such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.


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