The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2003
Filed:
Oct. 04, 1999
Applicant:
Inventors:
Valérie Legrand, Strasbourg, FR;
Majid Mehtali, Illkirch Graffenstaden, FR;
Pierre Boulanger, Montpellier, FR;
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/5861 ; C12N 1/586 ;
U.S. Cl.
CPC ...
C12N 1/5861 ; C12N 1/586 ;
Abstract
The invention relates to an adenovirus fiber modified by the mutation of one or more residues. The residues are directed towards the natural cell receptor in the three-dimensional structure of said adenovirus. The invention further relates to a DNA fragment, and expression vector, and a cell line expressing said fiber, and also concerns an adenovirus, the process for producing this type of adenovirus, and a infectable host cell, as well as their therapeutic application and a corresponding pharmaceutical composition.