The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2003

Filed:

Oct. 13, 1998
Applicant:
Inventors:

Trevor Percival Castor, Arlington, MA (US);

Glenn Thomas Hong, Westborough, MA (US);

Assignee:

Aphios Corporation, Woburn, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07G 1/700 ; C12P 3/506 ; C12Q 1/02 ;
U.S. Cl.
CPC ...
C07G 1/700 ; C12P 3/506 ; C12Q 1/02 ;
Abstract

Supercritical and near critical fluids are used to fractionate biomass materials such as microbial cells in two steps. In the first step, the biomass is exposed to elevated pressure supercritical or near critical fluid to bring about disruption of the biomass to liberate structural biomass constituents. In the second step, the disrupted biomass is subjected to a multiplicity of supercritical or near critical fluid extraction steps, with different solvation conditions used for each fraction. Thus, fractionation of the biomass to obtain one or more compounds is effected. Different solvation properties are obtained using different temperatures, pressures and/or modifier concentrations.


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