The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2003
Filed:
May. 27, 1999
Applicant:
Inventors:
Paul G. Grothaus, Mililani, HI (US);
Dana E. Davis, San Jose, CA (US);
Sean O'Malley, Honolulu, HI (US);
Assignee:
Hawaii Biotechnology Group, Inc., Aiea, HI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/3543 ; C12Q 1/37 ; C12N 9/50 ; A61K 3/800 ; C07D / ;
U.S. Cl.
CPC ...
G01N 3/3543 ; C12Q 1/37 ; C12N 9/50 ; A61K 3/800 ; C07D / ;
Abstract
An assay is disclosed for determining whether a test compound modulates the activity of an enzyme having a metallated active site. The assay method employs a comparison of the binding ability of the metallated and unmetallated forms of the enzyme to the test compound.