The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2003
Filed:
Jul. 21, 2000
Applicant:
Inventors:
Ronald N. Zuckermann, Berkeley, CA (US);
Chin-Yi Huang, Fremont, CA (US);
John E. Murphy, Oakland, CA (US);
Tetsuo Uno, San Francisco, CA (US);
Assignee:
Chiron Corporation, Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 ; C08K 5/20 ; C12N 1/500 ; C07C / ;
U.S. Cl.
CPC ...
A61K 9/127 ; C08K 5/20 ; C12N 1/500 ; C07C / ;
Abstract
In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof. Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.