The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2003

Filed:

Sep. 28, 1999
Applicant:
Inventors:

Andrew D. Sutton, Ruddington, GB;

Richard A. Johnson, West Bridgford, GB;

Peter J. Senior, Near Melbourne, GB;

David Heath, The Park, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/900 ; A61B 8/00 ; A61B 8/02 ;
U.S. Cl.
CPC ...
A61K 4/900 ; A61B 8/00 ; A61B 8/02 ;
Abstract

Microcapsules are prepared by a process comprising the steps of (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microcapsules and (ii) reducing the water-solubility of at least the outside of the intermediate microcapsules. Suitable wall-forming materials include proteins such as albumin and gelatin. The microcapsules have walls of 40-500 nm thick and are useful in ultrasonic imaging. The control of median size, size distribution and degree of insolubilization and cross-linking of the wall-forming material allows novel microsphere preparations to be produced.


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