The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2003
Filed:
Mar. 15, 2000
Applicant:
Inventors:
Paul F. Goetinck, Boston, MA (US);
Peter C. Baciu, Laguna Niguel, CA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/400 ;
U.S. Cl.
CPC ...
C07K 1/400 ;
Abstract
The present invention relates to a gene encoding a novel protein, syndecan-4 binding protein (S4BP), which binds to syndecan-4. S4BP polypeptides play a role in cell matrix interactions. Described herein are isolated and antisense nucleic acids molecules, recombinant expression vectors, host cells and non-human transgenic animals containing an insertion or a disruption of the S4BP gene. Diagnostic, screening and therapeutic methods utilizing the compositions of the invention are also provided.