The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2003

Filed:

Apr. 27, 1998
Applicant:
Inventors:

Anthony P. Shuber, Milford, MA (US);

Stanley N. Lapidus, Bedford, NH (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ; G01N 3/300 ; C07H 2/102 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12P 1/934 ; C12Q 1/68 ; G01N 3/300 ; C07H 2/102 ; C07H 2/104 ;
Abstract

Methods are provided for selective nucleic acid sequence detection in single base primer extension reactions of high sensitivity. These methods are useful for detecting small amounts of mutant nucleic acid in a heterogeneous biological sample. These methods are particularly useful for identifying individuals with gene mutations indicative of early colorectal cancer.


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