The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2003
Filed:
Nov. 29, 1999
Applicant:
Inventors:
Joseph R. Moskal, Chicago, IL (US);
Hirotaka Yamamoto, Glenview, IL (US);
Assignee:
Chicago Institute of Neurosurgery and Neuroresearch, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/48 ; C07H 2/102 ; C07H 2/104 ; C07K 1/400 ;
U.S. Cl.
CPC ...
C12Q 1/48 ; C07H 2/102 ; C07H 2/104 ; C07K 1/400 ;
Abstract
The present invention relates to the prevention and treatment of a disease, preferably brain cancer, by administration of an isolated DNA molecule comprising a gene encoding a protein having glycosyltransferase activity to a cell involved in the disease which is preferably a glioblastoma cell. A method of treating brain cancer is provided in which a tumor cell is transfected either ex vivo or in vivo with a composition comprising a DNA molecule that encodes a protein having glycosyltransferase activity resulting in inhibition of the growth or function of that cell.