The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2003
Filed:
Mar. 23, 1999
Applicant:
Inventor:
Howard M. Shapiro, West Newton, MA (US);
Assignee:
Other;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/800 ; A61K 3/814 ;
U.S. Cl.
CPC ...
A61K 3/800 ; A61K 3/814 ;
Abstract
The present invention is drawn to methods of killing bacteria, including antibiotic resistant bacteria, by contacting said bacteria with a membrane permeabilizing compound or combination of compounds and a membrane impermeant toxic agent or combination of agents, resulting in the death of the bacteria without substantial injury to the infected host or patient. The present invention is also drawn to compositions and kits for effecting the method of the present invention. The present invention is further drawn to methods of rendering toxic agents such as toxic organic molecules, membrane impermeant for use in the methods and compositions of the present invention.