The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2003
Filed:
Jul. 08, 1999
Applicant:
Inventors:
Mary K. Hondalus, Northborough, MA (US);
Barry R. Bloom, Hastings on Hudson, NY (US);
William R. Jacobs, Jr., City Island, NY (US);
Assignee:
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/902 ; A61K 6/300 ; A61K 3/904 ; A61K 3/900 ; C12N 1/509 ;
U.S. Cl.
CPC ...
A61K 3/902 ; A61K 6/300 ; A61K 3/904 ; A61K 3/900 ; C12N 1/509 ;
Abstract
The present invention provides a recombinant mycobacterium that is auxotrophic for leucine. The present invention also provides a vaccine comprising a recombinant mycobacterium that is auxotrophic for leucine, as well as a method for treating or preventing tuberculosis in a subject comprising administering to the subject a recombinant mycobacterium that is auxotrophic for leucine in an amount effective to treat or prevent tuberculosis in the subject.