The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2003

Filed:

Mar. 16, 2001
Applicant:
Inventors:

Fumie Tanno, Niigata-ken, JP;

Sakae Obara, Niigata-ken, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/1715 ; C08B 1/108 ;
U.S. Cl.
CPC ...
A61K 3/1715 ; C08B 1/108 ;
Abstract

Provided are a solid preparation which rapidly disintegrates in the oral cavity when taken together with the saliva in the oral cavity or a small amount of water, can be prepared easily and has strength enough to retain its formability upon production or during distribution; and a production process of the solid preparation. Specifically, provided are a solid preparation comprising a low-substituted hydroxypropyl cellulose having a loose bulk density of 0.40 g/ml or greater and a tapped bulk density of 0.60 g/ml or greater, and a sugar and/or sugar alcohol; and a production process of the solid preparation. Also provided are a solid preparation comprising a low-substituted hydroxypropyl cellulose having a volume-average particle size as measured by the dry laser diffraction method of 25 &mgr;m or less which is obtained by pulverizing a low-substituted hydroxypropyl cellulose having a loose bulk density of 0.40 g/ml or greater, a tapped bulk density of 0.60 g/ml or greater, and a volume average particle size of 30 &mgr;m or greater—and a sugar and/or sugar alcohol; and a production process of the solid preparation.


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