The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2003
Filed:
Feb. 07, 2000
Applicant:
Inventors:
Stefan Stahl, Stockholm, SE;
Mathias Uhlen, Masvager, SE;
Per-Ake Nygren, Singelgrand, SE;
Per Jonasson, Sodermannagatan, SE;
Assignee:
Creative Peptides Sweden AB, Djusholm, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/517 ; C12N 1/563 ; A61K 3/828 ; C07K 1/462 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/517 ; C12N 1/563 ; A61K 3/828 ; C07K 1/462 ;
Abstract
The present invention provides a method of producing an insulin C-peptide, which comprises expressing in a host cell a multimeric polypeptide comprising multiple copies of the insulin C-peptide, and cleaving the expressed polypeptide to release single copies of the insulin C-peptide. Also provided are nucleic acid molecules, expression vectors and host cells, for use in such a method and the multimeric insulin C-peptide polypeptide expressed and cleaved in such a method.