The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2003
Filed:
Jul. 28, 1999
Eugen Ermantraut, Jena, DE;
Johann Michael Köhler, Golmsdorf, DE;
Torsten Schulz, Jena, DE;
Klaus Wohlfart, Laasan, DE;
Stefan Wölfl, Jena, DE;
Clondiag Chip Technologies GmbH, Jena, DE;
Abstract
The invention relates to a method for producing structured, self-organized molecular monolayers of individual molecular species. The invention is preferably used to create solid-phase bonded substance libraries. To this end, a) a substrate ( ) suitable for the first monolayer is provided; b) a microstructured polymer mask ( ) having openings is applied to the subtrate ( ) at least once in a defined direction. Said polymer mask ( ) is sufficiently thin and flexible for it to adhere to the substrate ( ) by adhesion, and the material selected for the polymer mask ( ) is chemically stable; c) the sandwich constituted by the substrate ( ) and polymer mask ( ) is flooded with a first agent corresponding to the intended use, so as to create at least one first molecular monolayer in the areas defined by the mask openings; c1) depending on the monolayer structure to be created step c) is repeated using the first agent or one or more additional agents; and d) after carrying out the step described in c) or the steps described in c) and c1), the polymer mask is pulled off after modification of the substrate surface areas which were left uncovered by the mask openings and were subjected to the agent or agents.