The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2003
Filed:
Apr. 13, 2001
Applicant:
Inventors:
James R. Dasch, Needham, MA (US);
M. Gary I. Riley, Cambridge, MA (US);
Assignee:
Alkermes Controlled Therapeutics, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/52 ; A61K 3/17052 ; A61K 3/802 ; A61K 3/818 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/52 ; A61K 3/17052 ; A61K 3/802 ; A61K 3/818 ;
Abstract
The present invention relates to a method for the sustained release in vivo of a biologically active agent comprising administering to a subject in need of treatment an effective amount of a sustained release composition comprising a biocompatible polymer having the biologically active agent incorporated therein, and a bisphosphonate wherein the bisphosphonate compound is present in an amount sufficient to modify the release profile of the biologically active agent from the sustained release composition. Pharmaceutical compositions suitable for use in the method of the invention are also disclosed.