The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2003
Filed:
Aug. 15, 2000
Applicant:
Inventors:
Susan L. Bernhard, Menlo Park, CA (US);
Robert Toso, Danville, CA (US);
Van Taiariol, Redwood City, CA (US);
Assignee:
Baxter International, Inc., Deerfield, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3543 ; G01N 3/344 ; G01N 3/002 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3543 ; G01N 3/344 ; G01N 3/002 ;
Abstract
This invention relates methods for conditioning affinity chromatography resins to decrease leaching of the ligand during purification. The methods involve incubating the resin in a buffered solution of a hydroxyalkylamine compound (e.g., ethanolamine) prior to use of the resin for an affinity purification. The treatment removes unstably bound ligand from the resin.