The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2003
Filed:
Oct. 17, 1997
Applicant:
Inventors:
Charles W. Rittershaus, Malden, MA (US);
Lawrence J. Thomas, Worcester, MA (US);
Assignee:
AVANT Immunotherapeutics, Inc., Needham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9385 ;
U.S. Cl.
CPC ...
A61K 3/9385 ;
Abstract
Conjugates are disclosed comprising a broad range helper T cell epitope portion and a B cell epitope portion from a cholesteryl ester transfer protein (CETP), which conjugates are capable of eliciting an immune response in an individual against the individual's endogenous CETP activity. The conjugates are useful in methods to inhibit CETP activity, to raise serum levels of high density lipoproteins, and to prevent or treat cardiovascular disease, such as atherosclerosis.