The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 22, 2003

Filed:

Jun. 18, 2001
Applicant:
Inventors:

Masako Tajima, Tokyo, JP;

Masakatsu Takanashi, Tokyo, JP;

Yukihisa Miyazawa, Tokyo, JP;

Toshio Takeshima, Tokyo, JP;

Kota Okinaga, Tokyo, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 ; C12N 7/01 ; A61K 3/800 ; C07K 2/00 ; C07K 4/00 ;
U.S. Cl.
CPC ...
C12N 7/00 ; C12N 7/01 ; A61K 3/800 ; C07K 2/00 ; C07K 4/00 ;
Abstract

An EBV strain infecting epithelial cells and a stomach cancer cell line cancerated by EBV are established to clarify the mechanism of canceration of epithelial cells into stomach cancer by EBV and to develop a chemotherapeutic agent for stomach cancer cancerated by EBV. Further, a stomach cancer cell line stably producing EBV-related antigens is established to develop a diagnostic drug for stomach cancer cancerated by EBV. According to the present invention, GTC-4 cell line was established through culture of stomach cancer tissues. GTC-4 produced the EBV strain infecting epithelial cells and simultaneously produced EBV-related antigens stably in the supernatant.


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