The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2003
Filed:
Aug. 23, 2001
Applicant:
Inventors:
Alireza Ebrahim, Aliso Viejo, CA (US);
Jayshree Parikh, Diamond Bar, CA (US);
Warren Eric Vanderslice, Fullerton, CA (US);
Assignee:
Bio-Rad Laboratories, Inc., Hercules, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/816 ; C07K 1/16 ;
U.S. Cl.
CPC ...
A61K 3/816 ; C07K 1/16 ;
Abstract
Low-concentration reference controls for C-reactive protein assays are prepared from higher-level starting materials by simple filtration using silica-type filter media formerly used for removing lipids. This process avoids the need for antibodies to capture the protein and resuspend it. Surprisingly, the removal of CRP by the silica-type filter media is selective toward CRP, having little or negligible effect on other proteins in the starting matrix, and accordingly little or negligible change in the total protein content.