The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2003

Filed:

Nov. 01, 2000
Applicant:
Inventors:

Gary L. Olson, Mountainside, NJ (US);

Christopher Self, West Caldwell, NJ (US);

Lily Lee, Edison, NJ (US);

Charles Michael Cook, Mendham, NJ (US);

Jens J. Birktoft, New York, NY (US);

Assignee:

Praecis Pharmaceuticals Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1336 ; A61K 3/808 ; C07D / ; C07K 7/06 ;
U.S. Cl.
CPC ...
A61K 3/1336 ; A61K 3/808 ; C07D / ; C07K 7/06 ;
Abstract

The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e.g., cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.


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