The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6548059 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 15, 2003

Filed:

Jan. 09, 2002
Applicant:
Inventors:

Nancy C. Joyce, Marlborough, MA (US);

Ko-Hua Chen, Taipei, TW;

Tadashi Senoo, Tochigi, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 6/300 ; A61K 3/900 ; C12N 5/08 ; C12N 5/00 ;
U.S. Cl.
CPC ...
A01N 6/300 ; A61K 3/900 ; C12N 5/08 ; C12N 5/00 ;
Abstract

Disclosed is a method of stimulating adult corneal endothelial cell proliferation, which includes incubation of corneal endothelium to a mitogen-containing medium and then to an agent that interrupts cell-cell contacts in the adult corneal endothelial cells, and subsequently, as needed, further incubation in the mitogen-containing medium. The cell-cell contact-interrupting agent is preferably a calcium chelator.


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