The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2003

Filed:

Aug. 25, 1999
Applicant:
Inventors:

Leslie David Bell, Thame, GB;

Keith Graham McCullagh, Princes Risborough, GB;

Alan George Porter, High Wycombe, GB;

Assignee:

Pharmacia Corporation, Peapack, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/400 ; C07K 1/600 ;
U.S. Cl.
CPC ...
C07K 1/400 ; C07K 1/600 ;
Abstract

Described is a new class of polypeptide cell modulators characterized by being composed of two covalently linked cell modulators in a linear polypeptide sequence. Such dual function polypeptides have new and particularly useful activities when the component polypeptide cell modulators are interferons, lymphokines or cytotoxins which act through different and specific cell receptors to initiate complementary biological activities. Also described is a peptide linker segment comprising a mouse IgG gamma “hinge” in which the four cysteines of the “hinge” have been converted to serines.


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