The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2003
Filed:
Nov. 08, 1999
Hermann Brugger, Illerkirchberg, DE;
Christian Rembe, Ulm, DE;
Raoul Bader, Mainz-Laubenheim, DE;
Eberhard P. Hofer, Lonsee, DE;
Hartmut Seliger, Elchingen, DE;
Merckle GmbH, Blaubeuren, DE;
Abstract
The invention relates to a device and to a process for the automatic synthesis of macromolecules on a tape-like substrate material ( ). The device has at least one synthesis module ( ) which can be sealed from the outside and comprises reaction chambers ( ) and fluid lines ( ) for filling and emptying the reaction chambers ( ) with and of reaction media, it being possible to introduce the substrate material ( ) into the synthesis module ( ) and bring it into contact with the reaction chambers ( ). Transport means ( ) which are intended to move the substrate material ( ) through a particular distance and can be actuated by a control device are furthermore provided. The invention also relates to the use of such a device for the synthesis of oligonucleotides bound on a functionalized substrate material, in particular the production of oligonucleotide libraries.