The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2003
Filed:
May. 02, 2001
Applicant:
Inventors:
Suresh C. Srivastava, Setauket, NY (US);
Zizhong Li, Upton, NY (US);
George Meinken, Middle Island, NY (US);
Assignee:
Brookhaven Science Associates, LLC, Upton, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/132 ; C07F 7/22 ; A61M 3/614 ;
U.S. Cl.
CPC ...
A61K 3/132 ; C07F 7/22 ; A61M 3/614 ;
Abstract
Novel methods are provided for the manufacture of Sn(Sn ) DTPA. The method allows the use of DTPA, a toxic chelating agent, in an approximately 1:1 ratio to Sn(Sn ) via either aqueous conditions, or using various organic solvents, such as methylene chloride. A pharmaceutical composition manufactured by the novel method is also provided, as well as methods for treatment of bone tumors and pain associated with bone cancer using the pharmaceutical composition of the invention.