The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2003

Filed:

Dec. 28, 2000
Applicant:
Inventors:

Isao Karube, Kanagawa, JP;

Takashi Saitoh, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 ;
U.S. Cl.
CPC ...
C12M 1/34 ;
Abstract

An apparatus for automatically measuring minute membrane potential, based on a technique developed for controlling a membrane denaturation reaction without using a physical shearing force, for example, a method of causing the destruction of membrane at a limited portion of a living membrane by making a stimulus, such as light and a compound activated by the stimulus react with each other in a membrane, such as a living membrane, this method being applied to a minute electrode to facilitate the insertion thereof into a cell, which has been difficult in the use of a minute metal electrode, and enable membrane potential in a cell to be measured easily, the minute metal electrode enabling the integration thereof and the development of a neural interface in the barrier-free technology.


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