The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2003

Filed:

May. 17, 1999
Applicant:
Inventors:
Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12P 2/106 ; C12N 1/500 ; C12N 1/20 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12P 2/106 ; C12N 1/500 ; C12N 1/20 ;
Abstract

The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.


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