The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2003
Filed:
Jul. 13, 2000
Kevin C. Dines, Poway, CA (US);
Timothy C. Gahman, Encinitas, CA (US);
Beverly E. Girten, Sunnyvale, CA (US);
Douglas L. Hitchin, San Diego, CA (US);
Kevin R. Holme, San Diego, CA (US);
Hengyuan Lang, San Diego, CA (US);
Sandra R. Slivka, San Diego, CA (US);
Karen J. Watson-Straughan, Encinitas, CA (US);
Ronald R. Tuttle, Escondido, CA (US);
Yazhong Pei, San Diego, CA (US);
Lion Bioscience AG, Heidelberg, DE;
Abstract
Methods for treating sexual dysfunction, such as erectile dysfunction or sexual arousal disorder, with a compound having the generic formula X —X -(D)Phe-Arg-(D)Trp-X . A particularly useful compound is HP-228, which has the formula Ac-Nle-Gln-His-(D)Phe-Arg-(D)Trp-Gly-NH . The invention also provides methods for selecting melanocortin receptor-3 ligands by determining whether a compound modulates the activity of MC-3 as an agonist or antagonist. These methods can be used to screen compound libraries for ligands to treat MC-3-associated conditions. Such conditions include sexual dysfunction, including erectile dysfunction and sexual arousal disorder.