The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2003

Filed:

Sep. 07, 1999
Applicant:
Inventors:

Pierre Alexandre Driguez, Toulouse, FR;

Philippe Duchaussoy, Toulouse, FR;

Jean Marc Herbert, Tourefeuille, FR;

Maurice Petitou, Paris Cedex, FR;

Constant Van Boeckel, Oss, NL;

Peter Grootenhuis, San Diego, CA (US);

Johannes Basten, Afferden, NL;

Cornelia Dreef-Tromp, Wijchen, NL;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/170 ; C07H 1/702 ;
U.S. Cl.
CPC ...
A61K 3/170 ; C07H 1/702 ;
Abstract

A synthetic polysaccharide including an antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin binding domain including a concatenation of 10-25 monosaccharide units selected from hexoses, pentoses or deoxy sugars of which all the hydroxyl groups are etherified by a C alkyl group or esterified in the form of sulpho groups, as well as salts and particularly pharmaceutically acceptable salts thereof, are disclosed.


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