The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2003
Filed:
Jul. 23, 2001
Constantin Polychronakos, Côte St-Luc, CA;
Petros Vafiadis, Laval, CA;
Rosemarie Grabs, Longueuil, CA;
Houria Ounissi-Benkalha, St-Laurent, CA;
McGill University, Montréal, CA;
Abstract
The present invention relates to a novel DNA assay for the diagnosis and/or prediction of autoimmune diabetes. The present invention relates to a DNA assay for the prediction of autoimmune diabetes in human subjects, which comprises the steps of a) obtaining a DNA sample from the subject and amplifying at least one class III allele of variable number of tandem repeats (VNTR) located upstream of the insulin gene (INS) which is associated with silencing of thymic insulin mRNA expression; and b) subjecting the sample to electrophoresis to identify the silencing class III allele.