The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2003

Filed:

Jul. 17, 1998
Applicant:
Inventors:

Darrel W. Stafford, Carrboro, NC (US);

Jin Li Chang, Chapel Hill, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/102 ; C12N 1/512 ; C12N 1/00 ; C12N 5/00 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12P 2/102 ; C12N 1/512 ; C12N 1/00 ; C12N 5/00 ; C12N 1/563 ;
Abstract

A non-naturally occuring Factor IX protein having an amino acid substitution at amino acid position 338 is provided. Preferred substitutions include the substitution of analanine, leucine, or valine for the arginine at amino acid position 338. Factor IX of the present invention is non-naturally occuring (e.g., does not contain only an arginine to proline substitution at amino acid position 338). Factor IX proteins of the invention are useful for facilitating blood clotting in subjects in need thereof, such as subjects afflicted with hemophilia B. Pharmaceutical formulations comprising Factor IX of the invention are provided, along with nucleic acids encoding the factor and vectors containing such nucleic acids.


Find Patent Forward Citations

Stafford, Darrel. (2003). Factor ix antihemophilic factor with increased clotting activity (U.S. Patent No. 6531298). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6531298

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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