The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2003
Filed:
Aug. 09, 2000
Applicant:
Inventors:
Ching-Ling Teng, Fremont, CA (US);
Charles Hsiao, Livermore, CA (US);
Joshua Gatts, Hayward, CA (US);
Assignee:
Impax Laboratories, Inc., Haywood, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/48 ; A61K 9/20 ; A61K 9/50 ; A61K 9/26 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/48 ; A61K 9/20 ; A61K 9/50 ; A61K 9/26 ;
Abstract
The present invention provides a drug delivery system for the oral administration of a hydrophobic active ingredient. The active ingredient's post-ingestion dissolution rate and its corresponding bioavailability can be optimized by intimately mixing a micronized hydrophobic drug with suitably sized inert particles to a dispersion that will facilitate desired bioavailability. In a particular embodiment, the hydrophobic active ingredient is fenofibrate. Suitably sized inert particles include microcrystalline cellulose and lactose. Dispersion may be monitored by microscopic visualization.