The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2003
Filed:
Jul. 16, 2001
Dirk D. Leysen, Lommel, BE;
Jaap J. van der Louw, En Oss, NL;
Robert Gerard Jules Marie Hanssen, Heesch, NL;
A. Anja Wiersma, He Elst, NL;
Akzo Nobel N.V., Arnhem, NL;
Abstract
The invention relates to 22S hydroxycholesta-8, 14-diene derivatives having general formula (I) wherein R is OR, OSO H or —NOR; with R being H, (C )alkyl or (C )acyl; each of R and R is independently hydrogen or (C )alkyl; R is hydrogen, (C )alkyl or (C )acyl; R is hydrogen; or R designates, together with R , an additional bond between the carbon atoms at which R and R are placed; R is hydrogen, hydroxy or halogen, or R designates, together with R , an additional bond between the carbon atoms at which R and R are placed; each or R and R is independently hydrogen or (C )alkyl, optionally substituted with OH, (C )alkoxy, or halogen; or a pharmaceutically acceptable salt thereof. The compounds of the invention have meiosis activating activity and can be used for the control of fertility.