The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2003
Filed:
Jul. 07, 2000
Applicant:
Inventors:
Vivian W. Lee, Alamo, CA (US);
Kris P. Antonsen, Berkeley, CA (US);
Assignee:
PPL (Holdings) Limited, London, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/00 ;
U.S. Cl.
CPC ...
C07K 1/00 ;
Abstract
A method for purifying human or other alpha-l proteinase inhibitor (&agr; -PI) from a solution (which may be derived from the milk of a transgenic animal expressing the &agr; -PI) which comprises contacting the solution with a cation exchange substrate under conditions sufficient to bind non-tg-&agr; -PI contaminants to the substrate while not substantially binding tg &agr; -PI to the substrate. Using the preferred embodiment, the purified tg &agr; -PI contains as little as 40 pg non-&agr; -PI-whey protein per mg total protein.