The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2003
Filed:
Feb. 16, 2001
Richard E Olson, Wilmington, DE (US);
Thomas P Maduskuie, Wilmington, DE (US);
Lorin Andrew Thompson, Wilmington, DE (US);
Andrew J Tebben, Wallingford, PA (US);
Nenghui Wang, Newark, DE (US);
Wei Deng, Wilmington, DE (US);
Hong Liu, Glen Mills, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
This invention relates to novel carbocycles and heterocycles having drug and bio-affecting properties, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A&bgr;-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to &bgr;-amyloid production such as Alzheimer's disease and Down's Syndrome.