The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2003

Filed:

Oct. 29, 1998
Applicant:
Inventors:

Erik S. Falck-Pedersen, Dobbs Ferry, NY (US);

Keith Elkon, Larchmont, NY (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; A61K 3/800 ; C12N 1/563 ; C12N 1/585 ; C07K 1/400 ;
U.S. Cl.
CPC ...
A61K 4/800 ; A61K 3/800 ; C12N 1/563 ; C12N 1/585 ; C07K 1/400 ;
Abstract

The present invention provides, among other things, a method of inhibiting an immune response to a recombinant vector, such as a viral vector, specifically an adenoviral vector. The method comprises contacting a cell with (i) a recombinant vector, preferably a viral vector, most preferably an adenoviral vector, comprising a transgene and (ii) a means of inhibiting an immune response to the recombinant vector selected from the group consisting of a TNF receptor fusion protein, a Fas receptor fusion protein, an IFN receptor fusion protein, a gene encoding a TNF receptor fusion protein, a gene encoding a Fas receptor fusion protein, and a gene encoding an IFN receptor fusion protein, whereupon an immune response to the recombinant vector is inhibited. In this regard, the present invention also provides a recombinant vector and a composition for use in the method.


Find Patent Forward Citations

Falck-Pedersen, Erik. (2003). Method of inhibiting and immune response to a recombinant vector (U.S. Patent No. 6525029). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6525029

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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