The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2003
Filed:
Apr. 02, 1999
David Scott Edwards, Burlington, MA (US);
Milind Rajopadhye, Westford, MA (US);
Bristol-Myers Squibb Pharma Company, Princeton, NJ (US);
Abstract
The present invention provides novel radiopharmaceuticals comprising one to three pentapeptides, X X X X X , independently attached to a metal chelator or bonding moiety, C , to which is attached a Tc-99m, Re-186, or Re-188, optionally further comprising a linking group, L , between-the peptides and the chelator or bonding moiety. The pentapeptide sequence binds to the tuftsin receptor and is attached at the N-terminus to L or C . These radiopharmaceuticals are useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and methods of diagnosing diseases associated with infection or inflammation in patients in need of such diagnosis.