Compounds

Abstract

The invention provides compounds of general formula (I) wherein: R represents optionally substituted, C -C alkyl or optionally substituted 3- to 10-membered saturated or unsaturated ring system comprising up to two ring carbon atoms that form carbonyl groups and comprising up to 4 ring heteroatoms independently selected from nitrogen, oxygen and sulfur; m is 0-1; Q represents OCH , C -C alkylene or C -C alkenylene; T represents C(O)NH, or when m is 0, T may additionally represent a bond or NH, or when m is 1 and Q represents C -C alkylene, T may additionally represent NH; n is 1-4; each R and R independently represents H or C -C alkyl; V represents N, and W represents N or CH; X represents O, C(O), CH(OH), SO , NH or N(C -C alkyl), provided that when W represents N, then X represents either C(O) or SO and when W represents CH, then X is other than SO ; R represents optionally substituted phenyl; R and R each independently represent H, C -C alkyl or hydroxyC -C alkyl, or R and R together with the nitrogen atom to which they are attached form a 4- to 7-membered saturated heterocyclic ring; R and R each independently represent H or C -C alkyl; and R represents OH or —NR R ; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.